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M94A2718.TXT
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1994-10-25
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Document 2718
DOCN M94A2718
TI An in vitro qualitative assay for the detection of antibodies to HIV
type 1/2 contained in human saliva.
DT 9412
AU Chakrabarti T; Mukherjee K; Majumder K; Paul S; Chakrabarty MS; Virology
Department, School of Tropical Medicine, Calcutta.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):240 (abstract no. PB0391). Unique
Identifier : AIDSLINE ICA10/94369857
AB OBJECTIVE: There are ample evidences that saliva contain secretary--ab
against host of infections. Therefore saliva has been recommended as a
non invasive, safe and effective alternative to serum for HIV-ab
testings. The present study aims for a comparative evaluation of ab
detection by serum and saliva specimen in laboratory for diagnosis of
HIV infection in the Indian situation. METHODS: Saliva is collected from
a number of confirm cases of HIV infected persons by using a rayon ball
which placed in the mouth, paying particular attention to the area
between the teeth and gums, until it is completely saturated with saliva
and collected in a collection device. RESULTS: As the study does not
belong to routine screening system but it was undertaken only to see its
credibility and accountability compared to Western Blot system. Some
seronegative sera were also included in the test as control. DISCUSSION
AND CONCLUSIONS: Following the study of 42 test sera the workers came to
the conclusion that the test apart from its simplicity and
reproducibility was almost free from any false positive or false
negative reaction. Other informations are expected to be available from
the study for presentation in the scientific session of the conference.
DE AIDS Serodiagnosis/*METHODS Blotting, Western Human HIV
Antibodies/*ANALYSIS HIV Seronegativity/IMMUNOLOGY HIV
Seropositivity/*DIAGNOSIS/IMMUNOLOGY HIV-1/*IMMUNOLOGY
HIV-2/*IMMUNOLOGY Predictive Value of Tests Saliva/*IMMUNOLOGY
MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).